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 CARDIORISK Consortium

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SEVENTH FRAMEWORK PROGRAMME

Dissemination and Publications

CARDIORISK publications

Below you can find the (peer reviewed) publications resulted from Cardiorisk listed in alphabetical order.

Andratschke N, Maurer J,  Molls M and Trott KR. Review Late radiation-induced heart disease after radiotherapy. Clinical importance, radiobiological mechanisms and strategies of prevention. Radiotherapy and Oncology 2010in press. Link to abstract.

Elsner L, Flügge PF, Lozano J, Muppala V, Eiz-Vesper B, Demiroglu SY, Malzahn D, Herrmann T, Brunner E, Bickeböller H, Multhoff G, Walter L, Dressel R. The endogenous danger signals HSP70 a.  MICA cooperate in the activation of cytotoxic effector functions of NK cells. J Cell Mol Med. 2010 Apr;14(4):992-1002. Link to abstract.

Gehrmann M, Schilling D, Molls M, Multhoff G. Radiation induced stress proteins. Int J Clin Pharmacol Ther. 2010 Jul;48(7):492-3. Link to abstract.

Hendry JH, Akahoshi M, Wang LS, Lipshultz SE, Stewart FA, Trott KR. Radiation-induced cardiovascular injury. Radiat Environ Byophys 2008. 47: 189-193.  Link to abstract.

Hildebrandt G. Non-cancer diseases and non-targeted effects. Mutat Res. 2010 May 1;687(1-2):73-7. Link to abstract.

Horváth I, Multhoff G, Sonnleitner A, Vígh L. Membrane-associated stress proteins: more than simply chaperones. Biochim Biophys Acta. 2008 Jul-Aug;1778(7-8):1653-64. Link to abstract.

Hoving S, Heeneman S, Gijbels MJ, te Poele JA, Russell NS, Daemen MJ, Stewart FA. Single-dose and fractionated irradiation promote initiation and progression of atherosclerosis and induce an inflammatory plaque phenotype in ApoE-/- mice. Int J Radiat Oncol Biol Phys. 2008 Jul 1;71(3):848-57. Link to abstract.

Hoving S, Heeneman S, Gijbels MJ, te Poele JA, Bolla M, Pol JF, Simons MY, Russell NS, Daemen MJ, Stewart FA. NO-donating aspirin and aspirin partially inhibit age-related atherosclerosis but not radiation-induced atherosclerosis in ApoE null mice. PLoS One. 2010 Sep 21;5(9):e12874. Link to abstract.

Kruse JJ, Floot BG, te Poele JA, Russell NS, Stewart FA. Radiation-induced activation of TGF-beta signaling pathways in relation to vascular damage in mouse kidneys. Radiat Res. 2009 Feb;171(2):188-97. Link to abstract.

Milani V, Stangl S, Issels R, Gehrmann M, Wagner B, Hube K, Mayr D, Hiddemann W, Molls M, Multhoff G. Anti-tumor activity of patient-derived NK cells after cell-based immunotherapy - a case report. Journal of Translational Medicine 2009, 7:50. Link to abstract.  

Muthana M, Multhoff G, Pockley AG. Tumour infiltrating host cells and their significance for hyperthermia. Int J Hyperthermia. Int J Hyperthermia. 2010;26(3):247-55. Link to abstract.

Multhoff G. Hyperthermia classic commentary: Activation of natural killer (NK) cells by heat shock protein 70. Int J Hyperthermia. 2002 Nov-Dec;18(6):576-85. Link to abstract.

Riederer I, Sievert W, Eissner G, Molls M, Multhoff G. Irradiation-Induced Up-Regulation of HLA-E on Macrovascular Endothelial Cells Confers Protection against Killing by Activated Natural Killer Cells. PLoS One. 2010; 5(12): e15339. Link to abstract.

Russell NS, Hoving S, Heeneman S,  Daemen MJ, Stewart FA. Novel insights into pathological changes in muscular arteries of radiotherapy patients. Radiotherapy and Oncology 2009. 92: 477-483. Link to abstract.

Scharpfenecker M, Floot B, Russell NS, Ten Dijke P, Stewart FA. Endoglin haploinsufficiency reduces radiation-induced fibrosis and telangiectasia formation in mouse kidney. Radiother Oncol. 2009 Sep;92(3):484-91. Link to abstact.

Scharpfenecker M, Kruse JJ, Sprong D, Russell NS, Ten Dijke P, Stewart FA. Ionizing radiation shifts the PAI-1/ID-1 balance and activates NOTCH signaling in endothelial cells. International Journal of Radiation Oncology, Biology and Physics 2009. 73: 506-513.  Link to abstract.

Schilling D, Gehrmann M, Steienm C, DeMaio A, Pockley AG, Abend M, Molls M, Multhoff G. Binding of Hsp70 to extracellular PS promotes killing of normoxic and hypoxic tumor cells. FASEB J. 2009 Aug;23(8):2467-77. Link to abstract.

Stangl S, Themelis G, Friedrich L, Ntziachristos V, Sarantopoulos A, Molls M, Skerra A, Multhoff G. Detection of irradiation-induced, membrane heat shock protein 70 (Hsp70) in mouse tumors using Hsp70 Fab fragment. Radiother Oncol. 2011 Jun;99(3):313-6. Epub 2011 Jun 23. Link to abstract.

Stangl S, A, Multhoff G et al.. Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody. PNAS 2011. 108 (2):733 - 738. Link to abstract.

Stangl S, Multhoff G et al.. In vivo imaging of CT26 mouse tumors by using cmHsp70.1 monoclonal antibody. J. Cell. Mol. Med. 2011. 15 (4): 874 - 877. Link to abstract.

Stewart F, Doerr W et al. Milestones in normal tissue radiation biology over the past 50 years. Int J Radiat Biol. 2009 Jul;85(7):574-86. Link to abstract.

Stewart FA, Hoving S, Russell NS. Vascular damage as an underlying mechanism of cardiac and cerebraltoxicity in irradiated cancer patients. Radiat Res. 2010 Aug 30. [Epub ahead of print]. Link to abstract.

Pluder F, Barjaktarovic Z, Azimzadeh O, Mörtl S, Krämer A, Steininger S, Sarioglu H, Leszczynski D, Nylund R, Hakanen A, Sriharshan A, Atkinson MJ, Tapio S. Low-dose irradiation causes rapid alterations to the proteome of the human endothelial cell line EA.hy926. Environ Biophys. 2011 Mar;50(1):155-66. Epub 2010 Nov 23. Link to abstract.

Dissemination and Publications